Caricamento...

Ligand Bias at Metabotropic Glutamate 1a Receptors: Molecular Determinants That Distinguish β-Arrestin-Mediated from G Protein-Mediated Signaling

The metabotropic glutamate 1a (mGlu1a) receptor is a G protein-coupled receptor linked with phosphoinositide (PI) hydrolysis and with β-arrestin-1-mediated sustained extracellular signal-regulated kinase (ERK) phosphorylation and cytoprotective signaling. Previously, we reported the existence of lig...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Emery, Andrew C., DiRaddo, John O., Miller, Eric, Hathaway, Hannah A., Pshenichkin, Sergey, Takoudjou, Guy Rodrigue, Grajkowska, Ewa, Yasuda, Robert P., Wolfe, Barry B., Wroblewski, Jarda T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2012
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400838/
https://ncbi.nlm.nih.gov/pubmed/22584219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.078444
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !