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The Protective Signaling of Metabotropic Glutamate Receptor 1 Is Mediated by Sustained, β-Arrestin-1-dependent ERK Phosphorylation

Metabotropic glutamate receptor 1 (mGlu1) is a G protein-coupled receptor that enhances the hydrolysis of membrane phosphoinositides. In addition to its role in synaptic transmission and plasticity, mGlu1 has been shown to be involved in neuroprotection and neurodegeneration. In this capacity, we ha...

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書誌詳細
主要な著者: Emery, Andrew C., Pshenichkin, Sergey, Takoudjou, Guy Rodrigue, Grajkowska, Ewa, Wolfe, Barry B., Wroblewski, Jarda T.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924003/
https://ncbi.nlm.nih.gov/pubmed/20566651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.139899
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