Suppression of Autophagy in Osteocytes Does Not Modify the Adverse Effects of Glucocorticoids on Cortical Bone

Glucocorticoid excess decreases bone mass and strength in part by acting directly on osteoblasts and osteocytes, but the mechanisms remain unclear. Macroautophagy (herein referred to as autophagy) is a lysosome-based recycling pathway that promotes the turnover of intracellular components and can pr...

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Publicat a:Bone
Autors principals: Piemontese, Marilina, Onal, Melda, Xiong, Jinhu, Wang, Yiying, Almeida, Maria, Thostenson, Jeff D., Weinstein, Robert S., Manolagas, Stavros C., O’Brien, Charles A.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387016/
https://ncbi.nlm.nih.gov/pubmed/25700544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2015.02.005
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