Suppression of Autophagy in Osteocytes Does Not Modify the Adverse Effects of Glucocorticoids on Cortical Bone

Glucocorticoid excess decreases bone mass and strength in part by acting directly on osteoblasts and osteocytes, but the mechanisms remain unclear. Macroautophagy (herein referred to as autophagy) is a lysosome-based recycling pathway that promotes the turnover of intracellular components and can pr...

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Enregistré dans:
Détails bibliographiques
Publié dans:Bone
Auteurs principaux: Piemontese, Marilina, Onal, Melda, Xiong, Jinhu, Wang, Yiying, Almeida, Maria, Thostenson, Jeff D., Weinstein, Robert S., Manolagas, Stavros C., O’Brien, Charles A.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387016/
https://ncbi.nlm.nih.gov/pubmed/25700544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2015.02.005
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