Developmental Regulation and Induction of Cytochrome P450 2W1, an Enzyme Expressed in Colon Tumors

Cytochrome P450 2W1 (CYP2W1) is expressed predominantly in colorectal and also in hepatic tumors, whereas the levels are insignificant in the corresponding normal human adult tissues. CYP2W1 has been proposed as an attractive target for colorectal cancer (CRC) therapy by exploiting its ability to ac...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Choong, Eva, Guo, Jia, Persson, Anna, Virding, Susanne, Johansson, Inger, Mkrtchian, Souren, Ingelman-Sundberg, Magnus
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386763/
https://ncbi.nlm.nih.gov/pubmed/25844926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122820
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