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Combination Metronomic Oral Topotecan and Pazopanib: A Pharmacokinetic Study in Cancer Patients with Gynecological Cancer
BACKGROUND: Combination metronomic topotecan plus pazopanib is active against preclinical models of gynecologic cancer. Both agents are substrates for ATP-binding cassette family transporters so there is an increased likelihood for pharmacokinetic (PK) drug drug interactions. PATIENTS AND METHODS: P...
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| Udgivet i: | Anticancer Res |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4386652/ https://ncbi.nlm.nih.gov/pubmed/24023315 |
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