Flexibility in the Receptor-Binding Domain of the Enzymatic Colicin E9 Is Required for Toxicity against Escherichia coli Cells

The events that occur after the binding of the enzymatic E colicins to Escherichia coli BtuB receptors that lead to translocation of the cytotoxic domain into the periplasmic space and, ultimately, cell killing are poorly understood. It has been suggested that unfolding of the coiled-coil BtuB recep...

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Bibliografiska uppgifter
Huvudupphovsmän: Penfold, Christopher N., Healy, Bryan, Housden, Nicholas G., Boetzel, Ruth, Vankemmelbeke, Mireille, Moore, Geoffrey R., Kleanthous, Colin, James, Richard
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2004
Ämnen:
Enzymes and Proteins
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC438598/
https://ncbi.nlm.nih.gov/pubmed/15231784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.14.4520-4527.2004
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