Flexibility in the Receptor-Binding Domain of the Enzymatic Colicin E9 Is Required for Toxicity against Escherichia coli Cells

The events that occur after the binding of the enzymatic E colicins to Escherichia coli BtuB receptors that lead to translocation of the cytotoxic domain into the periplasmic space and, ultimately, cell killing are poorly understood. It has been suggested that unfolding of the coiled-coil BtuB recep...

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Detalhes bibliográficos
Main Authors: Penfold, Christopher N., Healy, Bryan, Housden, Nicholas G., Boetzel, Ruth, Vankemmelbeke, Mireille, Moore, Geoffrey R., Kleanthous, Colin, James, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Enzymes and Proteins
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC438598/
https://ncbi.nlm.nih.gov/pubmed/15231784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.14.4520-4527.2004
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