Flexibility in the Receptor-Binding Domain of the Enzymatic Colicin E9 Is Required for Toxicity against Escherichia coli Cells

The events that occur after the binding of the enzymatic E colicins to Escherichia coli BtuB receptors that lead to translocation of the cytotoxic domain into the periplasmic space and, ultimately, cell killing are poorly understood. It has been suggested that unfolding of the coiled-coil BtuB recep...

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Bibliografiske detaljer
Main Authors: Penfold, Christopher N., Healy, Bryan, Housden, Nicholas G., Boetzel, Ruth, Vankemmelbeke, Mireille, Moore, Geoffrey R., Kleanthous, Colin, James, Richard
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Enzymes and Proteins
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC438598/
https://ncbi.nlm.nih.gov/pubmed/15231784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.14.4520-4527.2004
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