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Immunity protein release from a cell-bound nuclease colicin complex requires global conformational rearrangement

Nuclease colicins bind their target receptor BtuB in the outer membrane of sensitive Escherichia coli cells in the form of a high-affinity complex with their cognate immunity proteins. The release of the immunity protein from the colicin complex is a prerequisite for cell entry of the colicin and oc...

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Detalhes bibliográficos
Main Authors: Vankemmelbeke, Mireille, Housden, Nicholas G, James, Richard, Kleanthous, Colin, Penfold, Christopher N
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831645/
https://ncbi.nlm.nih.gov/pubmed/24039240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.122
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