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Interaction of Nuclease Colicins with Membranes: Insertion Depth Correlates with Bilayer Perturbation

BACKGROUND: Protein transport across cellular membranes is an important aspect of toxin biology. Escherichia coli cell killing by nuclease colicins occurs through DNA (DNases) or RNA (RNases) hydrolysis and to this end their cytotoxic domains require transportation across two sets of membranes. In o...

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Hlavní autoři: Vankemmelbeke, Mireille, O′Shea, Paul, James, Richard, Penfold, Christopher N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460906/
https://ncbi.nlm.nih.gov/pubmed/23029560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046656
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