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Interaction of Nuclease Colicins with Membranes: Insertion Depth Correlates with Bilayer Perturbation

BACKGROUND: Protein transport across cellular membranes is an important aspect of toxin biology. Escherichia coli cell killing by nuclease colicins occurs through DNA (DNases) or RNA (RNases) hydrolysis and to this end their cytotoxic domains require transportation across two sets of membranes. In o...

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Detalhes bibliográficos
Main Authors: Vankemmelbeke, Mireille, O′Shea, Paul, James, Richard, Penfold, Christopher N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460906/
https://ncbi.nlm.nih.gov/pubmed/23029560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046656
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