Loss of fibroblast growth factor 21 action induces insulin resistance, pancreatic islet hyperplasia and dysfunction in mice

Fibroblast growth factor (FGF) 21 is an endocrine factor that normalizes glucose homeostasis and reduces insulin resistance in diabetes. Although the pancreas is an FGF21 target organ, its role in pancreatic islets remains obscure. This study aimed to elucidate the physiological role of FGF21 in pan...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: So, W Y, Cheng, Q, Xu, A, Lam, K S L, Leung, P S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385948/
https://ncbi.nlm.nih.gov/pubmed/25811804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.80
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