Loss of fibroblast growth factor 21 action induces insulin resistance, pancreatic islet hyperplasia and dysfunction in mice

Fibroblast growth factor (FGF) 21 is an endocrine factor that normalizes glucose homeostasis and reduces insulin resistance in diabetes. Although the pancreas is an FGF21 target organ, its role in pancreatic islets remains obscure. This study aimed to elucidate the physiological role of FGF21 in pan...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: So, W Y, Cheng, Q, Xu, A, Lam, K S L, Leung, P S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385948/
https://ncbi.nlm.nih.gov/pubmed/25811804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.80
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