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Alcohol ingestion induces pancreatic islet dysfunction and apoptosis via mediation of FGF21 resistance
BACKGROUND: Disruption of β-cell insulin secretion and viability caused by excessive ethanol consumption increases type 2 diabetes mellitus (T2DM) pathogenesis risk. Fibroblast growth factor 21 (FGF21) plays a significant role in regulating lipid and glucose homeostasis. Recently, FGF21, best known...
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| Publicat a: | Ann Transl Med |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
AME Publishing Company
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7186649/ https://ncbi.nlm.nih.gov/pubmed/32355754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2020.02.129 |
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