Reactive oxygen species and p21(Waf1/Cip1) are both essential for p53-mediated senescence of head and neck cancer cells

Treatment of head and neck squamous cell carcinoma, HNSCC, often requires multimodal therapy, including radiation therapy. The efficacy of radiotherapy in controlling locoregional recurrence, the most frequent cause of death from HNSCC, is critically important for patient survival. One potential bio...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Fitzgerald, A L, Osman, A A, Xie, T-X, Patel, A, Skinner, H, Sandulache, V, Myers, J N
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385922/
https://ncbi.nlm.nih.gov/pubmed/25766317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.44
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