Structural organization of the dynein-dynactin complex bound to microtubules

Cytoplasmic dynein associates with dynactin to drive cargo movement on microtubules, but the structure of the dynein-dynactin complex is unknown. Using electron microscopy, we determined the organization of native bovine dynein, dynactin, and the dynein-dynactin-microtubule quaternary complex. In th...

Full description

Saved in:
Bibliographic Details
Published in:Nat Struct Mol Biol
Main Authors: Chowdhury, Saikat, Ketcham, Stephanie A., Schroer, Trina A., Lander, Gabriel C.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385409/
https://ncbi.nlm.nih.gov/pubmed/25751425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2996
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items