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Dynactin 3D structure: Implications for assembly and dynein binding

The multisubunit protein complex, dynactin, is an essential component of the cytoplasmic dynein motor. High resolution structural work on dynactin and the dynein/dynactin supercomplex has been limited to small subunits and recombinant fragments that do not report fully on either ≈ 1 MDa assembly. In...

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Bibliographische Detailangaben
Hauptverfasser: Imai, Hiroshi, Narita, Akihiro, Maeda, Yuichiro, Schroer, Trina A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216434/
https://ncbi.nlm.nih.gov/pubmed/25046383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.07.010
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