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Structure of dynein-dynactin on microtubules shows tandem adaptor binding
Cytoplasmic dynein is a microtubule motor that is activated by its cofactor dynactin and a coiled-coil cargo adaptor(1–3). Up to two dynein dimers can be recruited per dynactin, and interactions between them affect their combined motile behaviour(4–6). Different coiled-coil adaptors are linked to di...
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| Udgivet i: | Nature |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2022
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7613678/ https://ncbi.nlm.nih.gov/pubmed/36071160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-022-05186-y |
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