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Structure of dynein-dynactin on microtubules shows tandem adaptor binding

Cytoplasmic dynein is a microtubule motor that is activated by its cofactor dynactin and a coiled-coil cargo adaptor(1–3). Up to two dynein dimers can be recruited per dynactin, and interactions between them affect their combined motile behaviour(4–6). Different coiled-coil adaptors are linked to di...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Chaaban, Sami, Carter, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2022
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613678/
https://ncbi.nlm.nih.gov/pubmed/36071160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-022-05186-y
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