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Structure and Functional Role of Dynein’s Microtubule-Binding Domain

Dynein motors move various cargos along microtubules within the cytoplasm and power the beating of cilia and flagella. An unusual feature of dynein is that its microtubule-binding domain (MTBD) is separated from its ring-shaped AAA+ adenosine triphosphatase (ATPase) domain by a 15-nanometer coiled-c...

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Detalhes bibliográficos
Main Authors: Carter, Andrew P., Garbarino, Joan E., Wilson-Kubalek, Elizabeth M., Shipley, Wesley E., Cho, Carol, Milligan, Ronald A., Vale, Ronald D., Gibbons, I. R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663340/
https://ncbi.nlm.nih.gov/pubmed/19074350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1164424
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