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Distinct cell cycle–dependent roles for dynactin and dynein at centrosomes

Centrosomal dynactin is required for normal microtubule anchoring and/or focusing independently of dynein. Dynactin is present at centrosomes throughout interphase, but dynein accumulates only during S and G(2) phases. Blocking dynein-based motility prevents recruitment of dynactin and dynein to cen...

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Detalhes bibliográficos
Main Authors: Quintyne, Nicholas J., Schroer, Trina A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173046/
https://ncbi.nlm.nih.gov/pubmed/12391026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200203089
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