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Structural organization of the dynein-dynactin complex bound to microtubules

Cytoplasmic dynein associates with dynactin to drive cargo movement on microtubules, but the structure of the dynein-dynactin complex is unknown. Using electron microscopy, we determined the organization of native bovine dynein, dynactin, and the dynein-dynactin-microtubule quaternary complex. In th...

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Detalles Bibliográficos
Publicado en:Nat Struct Mol Biol
Main Authors: Chowdhury, Saikat, Ketcham, Stephanie A., Schroer, Trina A., Lander, Gabriel C.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385409/
https://ncbi.nlm.nih.gov/pubmed/25751425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2996
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