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Validated LC-MS/MS method for the determination of 3-Hydroxflavone and its glucuronide in blood and bioequivalent buffers: Application to pharmacokinetic, absorption, and metabolism studies
The purpose of this study is to develop an UPLC-MS/MS method to quantify 3-hydroxy-flavone (3-HF) and its metabolite, 3-hydroxyflavone-glucuronide (3-HFG) from biological samples. A Waters BEH C(8) column was used with acetonitrile/0.1 % formic acid in water as mobile phases. The mass analysis was p...
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| Published in: | J Pharm Biomed Anal |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4385390/ https://ncbi.nlm.nih.gov/pubmed/23973631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2013.07.030 |
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