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Rab8, POSH, and TAK1 regulate synaptic growth in a Drosophila model of frontotemporal dementia
Mutations in genes essential for protein homeostasis have been identified in frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) patients. Why mature neurons should be particularly sensitive to such perturbations is unclear. We identified mutations in Rab8 in a genetic screen for e...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4384727/ https://ncbi.nlm.nih.gov/pubmed/25800055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201404066 |
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