miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a

Hematopoietic stem cells (HSCs) possess the ability to generate all hematopoietic cell types and to self-renew over long periods, but the mechanisms that regulate their unique properties are incompletely understood. Herein, we show that homozygous deletion of the miR-29a/b-1 bicistron results in dec...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Hu, Wenhuo, Dooley, James, Chung, Stephen S., Chandramohan, Dhruva, Cimmino, Luisa, Mukherjee, Siddhartha, Mason, Christopher E., de Strooper, Bart, Liston, Adrian, Park, Christopher Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383797/
https://ncbi.nlm.nih.gov/pubmed/25634742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-06-585273
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