Tumor endothelial cells with distinct patterns of TGFβ-driven endothelial-to-mesenchymal transition

Endothelial-to-mesenchymal transition (EndMT) occurs during development and underlies the pathophysiology of multiple diseases. In tumors, unscheduled EndMT generates cancer-associated myofibroblasts that fuel inflammation and fibrosis, and may contribute to vascular dysfunction that promotes tumor...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Xiao, Lin, Kim, Dae Joong, Davis, Clayton L., McCann, James V., Dunleavey, James M., Vanderlinden, Alissa, Xu, Nuo, Pattenden, Samantha G., Frye, Stephen V., Xu, Xia, Onaitis, Mark, Monaghan-Benson, Elizabeth, Burridge, Keith, Dudley, Andrew C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383705/
https://ncbi.nlm.nih.gov/pubmed/25634211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1616
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