Pancreatic Cancer-derived Exosomes Causes Paraneoplastic β-cell Dysfunction

BACKGROUND & AIMS: Pancreatic cancer (PC) frequently causes diabetes. We recently proposed adrenomedullin (AM) as a candidate mediator of pancreatic β-cell dysfunction in PC. How PC-derived AM reaches β-cells remote from the cancer to induce β-cell dysfunction is unknown. We tested a novel hypot...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Clin Cancer Res
Hlavní autoři: Javeed, Naureen, Sagar, Gunisha, Dutta, Shamit K., Smyrk, Thomas C., Lau, Julie S., Bhattacharya, Santanu, Truty, Mark, Petersen, Gloria M., Kaufman, Randal J., Chari, Suresh T., Mukhopadhyay, Debabrata
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383684/
https://ncbi.nlm.nih.gov/pubmed/25355928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2022
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky