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Characterization of the intrinsic activity for a novel class of cannabinoid receptor ligands: Indole Quinuclidine analogues

Our laboratory recently reported that a group of novel indole quinuclidine analogues bind with nanomolar affinity to cannabinoid type-1 and type-2 receptors. This study characterized the intrinsic activity of these compounds by determining whether they exhibit agonist, antagonist, or inverse agonist...

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Publicat a:Eur J Pharmacol
Autors principals: Franks, Lirit N., Ford, Benjamin M., Madadi, Nikhil R., Penthala, Narsimha R., Crooks, Peter A., Prather, Paul L.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383465/
https://ncbi.nlm.nih.gov/pubmed/24858620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2014.05.007
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