Proteolytic Disassembly of Viral Outer Capsid Proteins Is Crucial for Reovirus-Mediated Type-I Interferon Induction in Both Reovirus-Susceptible and Reovirus-Refractory Tumor Cells

Oncolytic reovirus induces innate immune responses, which contribute to the antitumor activity of reovirus, following in vivo application. Reovirus-induced innate immune responses have been relatively well characterized in immune cells and mouse embryonic fibroblasts cells; however, the mechanisms a...

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Dades bibliogràfiques
Publicat a:Biomed Res Int
Autors principals: Katayama, Yuki, Terasawa, Yuichi, Tachibana, Masashi, Mizuguchi, Hiroyuki, Sakurai, Fuminori
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383355/
https://ncbi.nlm.nih.gov/pubmed/25866783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/468457
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