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Proteolytic Disassembly Is a Critical Determinant for Reovirus Oncolysis

See page 1406 Mammalian ortheoreoviruses are currently being investigated as novel cancer therapeutics, but the cellular mechanisms that regulate susceptibility to reovirus oncolysis remain poorly understood. In this study, we present evidence that virion disassembly is a key determinant of reovirus...

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Bibliografiske detaljer
Udgivet i:Mol Ther
Main Authors: Alain, Tommy, Kim, Tom SY, Lun, XueQing, Liacini, Adelhamid, Schiff, Leslie A, Senger, Donna L, Forsyth, Peter A
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Gene Therapy. Published by Elsevier Inc. 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185731/
https://ncbi.nlm.nih.gov/pubmed/17519890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.mt.6300207
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