Molecular Determinants of Proteolytic Disassembly of the Reovirus Outer Capsid

Following attachment and internalization, mammalian reoviruses undergo intracellular proteolytic disassembly followed by viral penetration into the cytoplasm. The initiating event in reovirus disassembly is the cathepsin-mediated proteolytic degradation of viral outer capsid protein σ3. A single tyr...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Doyle, Joshua D., Danthi, Pranav, Kendall, Emily A., Ooms, Laura S., Wetzel, J. Denise, Dermody, Terence S.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2012
Sujets:
Microbiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318753/
https://ncbi.nlm.nih.gov/pubmed/22253447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.334854
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