Molecular Determinants of Proteolytic Disassembly of the Reovirus Outer Capsid

Following attachment and internalization, mammalian reoviruses undergo intracellular proteolytic disassembly followed by viral penetration into the cytoplasm. The initiating event in reovirus disassembly is the cathepsin-mediated proteolytic degradation of viral outer capsid protein σ3. A single tyr...

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Bibliografske podrobnosti
Main Authors: Doyle, Joshua D., Danthi, Pranav, Kendall, Emily A., Ooms, Laura S., Wetzel, J. Denise, Dermody, Terence S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Microbiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318753/
https://ncbi.nlm.nih.gov/pubmed/22253447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.334854
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