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Molecular Determinants of Proteolytic Disassembly of the Reovirus Outer Capsid

Following attachment and internalization, mammalian reoviruses undergo intracellular proteolytic disassembly followed by viral penetration into the cytoplasm. The initiating event in reovirus disassembly is the cathepsin-mediated proteolytic degradation of viral outer capsid protein σ3. A single tyr...

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Autors principals: Doyle, Joshua D., Danthi, Pranav, Kendall, Emily A., Ooms, Laura S., Wetzel, J. Denise, Dermody, Terence S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318753/
https://ncbi.nlm.nih.gov/pubmed/22253447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.334854
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