A Monoclonal Antibody Specific for Reovirus Outer-Capsid Protein ς3 Inhibits ς1-Mediated Hemagglutination by Steric Hindrance

Reovirus virions are nonenveloped icosahedral particles consisting of two concentric protein shells, termed outer capsid and core. Outer-capsid protein ς1 is the viral attachment protein and binds carbohydrate molecules on the surface of host cells. Monoclonal antibody (MAb) 4F2, which is specific f...

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Detalhes bibliográficos
Main Authors: Nason, Emma L., Wetzel, J. Denise, Mukherjee, S. K., Barton, Erik S., Prasad, B. V. Venkataram, Dermody, Terence S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114386/
https://ncbi.nlm.nih.gov/pubmed/11413330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.14.6625-6634.2001
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