Cleavage Susceptibility of Reovirus Attachment Protein ς1 during Proteolytic Disassembly of Virions Is Determined by a Sequence Polymorphism in the ς1 Neck

A requisite step in reovirus infection of the murine intestine is proteolysis of outer-capsid proteins to yield infectious subvirion particles (ISVPs). When converted to ISVPs by intestinal proteases, virions of reovirus strain type 3 Dearing (T3D) lose 90% of their original infectivity due to cleav...

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Bibliografiske detaljer
Main Authors: Chappell, James D., Barton, Erik S., Smith, Trent H., Baer, Geoffrey S., Duong, David T., Nibert, Max L., Dermody, Terence S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Animal Viruses
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC110170/
https://ncbi.nlm.nih.gov/pubmed/9733863
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