Reovirus-Induced Apoptosis Is Preceded by Increased Cellular Calpain Activity and Is Blocked by Calpain Inhibitors

The cellular pathways of apoptosis have not been fully characterized; however, calpain, a cytosolic calcium-activated cysteine protease, has been implicated in several forms of programmed cell death. Reoviruses induce apoptosis both in vitro and in vivo and serve as a model for studying virus-induce...

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Bibliografiske detaljer
Main Authors: Debiasi, Roberta L., Squier, Margaret K. T., Pike, Bobbi, Wynes, Murry, Dermody, Terence S., Cohen, J. John, Tyler, Kenneth L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC103876/
https://ncbi.nlm.nih.gov/pubmed/9847375
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