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Cleavage Susceptibility of Reovirus Attachment Protein ς1 during Proteolytic Disassembly of Virions Is Determined by a Sequence Polymorphism in the ς1 Neck

A requisite step in reovirus infection of the murine intestine is proteolysis of outer-capsid proteins to yield infectious subvirion particles (ISVPs). When converted to ISVPs by intestinal proteases, virions of reovirus strain type 3 Dearing (T3D) lose 90% of their original infectivity due to cleav...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Chappell, James D., Barton, Erik S., Smith, Trent H., Baer, Geoffrey S., Duong, David T., Nibert, Max L., Dermody, Terence S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1998
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110170/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9733863/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.10.8205-8213.1998
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