Molecular Determinants of Proteolytic Disassembly of the Reovirus Outer Capsid

Following attachment and internalization, mammalian reoviruses undergo intracellular proteolytic disassembly followed by viral penetration into the cytoplasm. The initiating event in reovirus disassembly is the cathepsin-mediated proteolytic degradation of viral outer capsid protein σ3. A single tyr...

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Hlavní autoři: Doyle, Joshua D., Danthi, Pranav, Kendall, Emily A., Ooms, Laura S., Wetzel, J. Denise, Dermody, Terence S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318753/
https://ncbi.nlm.nih.gov/pubmed/22253447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.334854
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