Translational diffusion of hydration water correlates with functional motions in folded and intrinsically disordered proteins

Hydration water is the natural matrix of biological macromolecules and is essential for their activity in cells. The coupling between water and protein dynamics has been intensively studied, yet it remains controversial. Here we combine protein perdeuteration, neutron scattering and molecular dynami...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Schirò, Giorgio, Fichou, Yann, Gallat, Francois-Xavier, Wood, Kathleen, Gabel, Frank, Moulin, Martine, Härtlein, Michael, Heyden, Matthias, Colletier, Jacques-Philippe, Orecchini, Andrea, Paciaroni, Alessandro, Wuttke, Joachim, Tobias, Douglas J., Weik, Martin
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Pub. Group 2015
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382692/
https://ncbi.nlm.nih.gov/pubmed/25774711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7490
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