Translational diffusion of hydration water correlates with functional motions in folded and intrinsically disordered proteins

Hydration water is the natural matrix of biological macromolecules and is essential for their activity in cells. The coupling between water and protein dynamics has been intensively studied, yet it remains controversial. Here we combine protein perdeuteration, neutron scattering and molecular dynami...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Schirò, Giorgio, Fichou, Yann, Gallat, Francois-Xavier, Wood, Kathleen, Gabel, Frank, Moulin, Martine, Härtlein, Michael, Heyden, Matthias, Colletier, Jacques-Philippe, Orecchini, Andrea, Paciaroni, Alessandro, Wuttke, Joachim, Tobias, Douglas J., Weik, Martin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Pub. Group 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382692/
https://ncbi.nlm.nih.gov/pubmed/25774711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7490
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