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Cardiac Findings and Events Observed in an Open-Label Clinical Trial of Tafamidis in Patients with non-Val30Met and non-Val122Ile Hereditary Transthyretin Amyloidosis

A phase 2, open-label study in 21 patients with non-Val30Met and non-Val122Ile hereditary transthyretin amyloidosis showed that tafamidis (20 mg daily for 12 months) stabilized these transthyretin variants. We assessed cardiac amyloid infiltration and cardiac abnormalities in this same study populat...

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Bibliographische Detailangaben
Veröffentlicht in:J Cardiovasc Transl Res
Hauptverfasser: Damy, Thibaud, Judge, Daniel P., Kristen, Arnt V., Berthet, Karine, Li, Huihua, Aarts, Janske
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382536/
https://ncbi.nlm.nih.gov/pubmed/25743445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12265-015-9613-9
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