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VEGF-C/VEGFR-3 Signaling Regulates Chemokine Gradients and Lymphocyte Migration from Tissues to Lymphatics
BACKGROUND: Circulation of leukocytes via blood, tissue and lymph is integral to adaptive immunity. Afferent lymphatics form CCL21 gradients to guide DC and T cells to lymphatics and then to draining lymph nodes (dLN). VEGF-C and VEGFR-3 are the major lymphatic growth factor and receptor. We hypothe...
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| 出版年: | Transplantation |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4382428/ https://ncbi.nlm.nih.gov/pubmed/25606800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000000561 |
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