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T-bet regulates natural Treg afferent lymphatic migration and suppressive function
T-bet is essential for nTreg to regulate Th1 inflammation, but whether T-bet controls other Treg functions after entering the inflammatory site, is unknown. In an islet allograft model, T-bet(−/−)nTreg but not iTreg failed to prolong graft survival as effectively as wild type Treg. T-bet(−/−) nTreg...
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| Publicat a: | J Immunol |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4779695/ https://ncbi.nlm.nih.gov/pubmed/26880765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502537 |
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