Mammalian target of rapamycin is essential for cardiomyocyte survival and heart development in mice

Mammalian target of rapamycin (mTOR) is a critical regulator of protein synthesis, cell proliferation and energy metabolism. As constitutive knockout of Mtor leads to embryonic lethality, the in vivo function of mTOR in perinatal development and postnatal growth of heart is not well defined. In this...

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Udgivet i:Biochem Biophys Res Commun
Main Authors: Zhang, Pengpeng, Shan, Tizhong, Liang, Xinrong, Deng, Changyan, Kuang, Shihuan
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382310/
https://ncbi.nlm.nih.gov/pubmed/25139234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.08.046
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