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Myostatin knockout drives browning of white adipose tissue through activating the AMPK-PGC1α-Fndc5 pathway in muscle
Myostatin (Mstn) is predominantly expressed in skeletal muscles and plays important roles in regulating muscle growth and development, as well as fat deposition. Mstn-knockout (Mstn(−/−)) mice exhibit increased muscle mass due to both hypertrophy and hyperplasia, and leaner body composition due to r...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3633817/ https://ncbi.nlm.nih.gov/pubmed/23362117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-225755 |
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