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Lkb1 is indispensable for skeletal muscle development, regeneration and satellite cell homeostasis
Stk11, commonly known as Lkb1, is a tumor suppressor that regulates cellular energy metabolism and stem cell function. Satellite cells are skeletal muscle resident stem cells that maintain postnatal muscle growth and repair. Here, we used MyoD(Cre)/Lkb1(flox/flox) mice (called MyoD-Lkb1) to delete L...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4198532/ https://ncbi.nlm.nih.gov/pubmed/25069613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1788 |
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