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Lkb1 is indispensable for skeletal muscle development, regeneration and satellite cell homeostasis

Stk11, commonly known as Lkb1, is a tumor suppressor that regulates cellular energy metabolism and stem cell function. Satellite cells are skeletal muscle resident stem cells that maintain postnatal muscle growth and repair. Here, we used MyoD(Cre)/Lkb1(flox/flox) mice (called MyoD-Lkb1) to delete L...

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Hlavní autoři: Shan, Tizhong, Zhang, Pengpeng, Liang, Xinrong, Bi, Pengpeng, Yue, Feng, Kuang, Shihuan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198532/
https://ncbi.nlm.nih.gov/pubmed/25069613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1788
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