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Mammalian target of rapamycin is essential for cardiomyocyte survival and heart development in mice

Mammalian target of rapamycin (mTOR) is a critical regulator of protein synthesis, cell proliferation and energy metabolism. As constitutive knockout of Mtor leads to embryonic lethality, the in vivo function of mTOR in perinatal development and postnatal growth of heart is not well defined. In this...

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Detaylı Bibliyografya
Yayımlandı:Biochem Biophys Res Commun
Asıl Yazarlar: Zhang, Pengpeng, Shan, Tizhong, Liang, Xinrong, Deng, Changyan, Kuang, Shihuan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382310/
https://ncbi.nlm.nih.gov/pubmed/25139234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.08.046
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