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Mammalian target of rapamycin is essential for cardiomyocyte survival and heart development in mice

Mammalian target of rapamycin (mTOR) is a critical regulator of protein synthesis, cell proliferation and energy metabolism. As constitutive knockout of Mtor leads to embryonic lethality, the in vivo function of mTOR in perinatal development and postnatal growth of heart is not well defined. In this...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Zhang, Pengpeng, Shan, Tizhong, Liang, Xinrong, Deng, Changyan, Kuang, Shihuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382310/
https://ncbi.nlm.nih.gov/pubmed/25139234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.08.046
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