Intronic locus determines SHROOM3 expression and potentiates renal allograft fibrosis

Fibrosis underlies the loss of renal function in patients with chronic kidney disease (CKD) and in kidney transplant recipients with chronic allograft nephropathy (CAN). Here, we studied the effect of an intronic SNP in SHROOM3, which has previously been linked to CKD, on the development of CAN in a...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Clin Invest
Κύριοι συγγραφείς: Menon, Madhav C., Chuang, Peter Y., Li, Zhengzhe, Wei, Chengguo, Zhang, Weijia, Luan, Yi, Yi, Zhengzi, Xiong, Huabao, Woytovich, Christopher, Greene, Ilana, Overbey, Jessica, Rosales, Ivy, Bagiella, Emilia, Chen, Rong, Ma, Meng, Li, Li, Ding, Wei, Djamali, Arjang, Saminego, Millagros, O’Connell, Philip J., Gallon, Lorenzo, Colvin, Robert, Schroppel, Bernd, He, John Cijiang, Murphy, Barbara
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Clinical Investigation 2014
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382250/
https://ncbi.nlm.nih.gov/pubmed/25437874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI76902
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