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Single-particle cryo-EM of the ryanodine receptor channel in an aqueous environment

Ryanodine receptors (RyRs) are tetrameric ligand-gated Ca(2+) release channels that are responsible for the increase of cytosolic Ca(2+) concentration leading to muscle contraction. Our current understanding of RyR channel gating and regulation is greatly limited due to the lack of a high-resolution...

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Vydáno v:Eur J Transl Myol
Hlavní autoři: Baker, Mariah R., Fan, Guizhen, Serysheva, Irina I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381806/
https://ncbi.nlm.nih.gov/pubmed/25844145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/bam.2015.1.35
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