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Cryo-EM structure of type 1 IP(3)R channel in a lipid bilayer

Type 1 inositol 1,4,5-trisphosphate receptor (IP(3)R1) is the predominant Ca(2+)-release channel in neurons. IP(3)R1 mediates Ca(2+) release from the endoplasmic reticulum into the cytosol and thereby is involved in many physiological processes. Here, we present the cryo-EM structures of full-length...

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Bibliografske podrobnosti
izdano v:Commun Biol
Main Authors: Baker, Mariah R., Fan, Guizhen, Seryshev, Alexander B., Agosto, Melina A., Baker, Matthew L., Serysheva, Irina I.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8149723/
https://ncbi.nlm.nih.gov/pubmed/34035440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02156-4
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