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Single-Particle Cryo-EM of the Ryanodine Receptor Channel in an Aqueous Environment

Ryanodine receptors (RyRs) are tetrameric ligand-gated Ca(2+) release channels that are responsible for the increase of cytosolic Ca(2+) concentration leading to muscle contraction. Our current understanding of RyR channel gating and regulation is greatly limited due to the lack of a high-resolution...

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Bibliographic Details
Published in:Eur J Transl Myol
Main Authors: Baker, Mariah R., Fan, Guizhen, Serysheva, Irina I.
Format: Artigo
Language:Inglês
Published: PAGEPress Publications, Pavia, Italy 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748972/
https://ncbi.nlm.nih.gov/pubmed/25844145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/ejtm.2015.4803
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