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Single-Particle Cryo-EM of Calcium Release Channels: Structural Validation

Few tools are available to determine the structure of large integral membrane proteins such as intracellular Ca(2+) release channels, RyRs and IP(3)Rs. Single particle cryo-EM can readily determine the structure of such channels to intermediate resolution, and can be used to quantitatively assess co...

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Autores principales: Ludtke, Steven J., Serysheva, Irina I.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805725/
https://ncbi.nlm.nih.gov/pubmed/23831288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2013.06.003
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