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Single-Particle Cryo-EM of Calcium Release Channels: Structural Validation
Few tools are available to determine the structure of large integral membrane proteins such as intracellular Ca(2+) release channels, RyRs and IP(3)Rs. Single particle cryo-EM can readily determine the structure of such channels to intermediate resolution, and can be used to quantitatively assess co...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3805725/ https://ncbi.nlm.nih.gov/pubmed/23831288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2013.06.003 |
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