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PPAR gamma activation is neuroprotective in a Drosophila model of ALS based on TDP-43
Amyotrophic Lateral Sclerosis (ALS) is a progressive neuromuscular disease for which there is no cure. We have previously developed a Drosophila model of ALS based on TDP-43 that recapitulates several aspects of disease pathophysiology. Using this model, we designed a drug screening strategy based o...
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| Publicado no: | Hum Mol Genet |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4381760/ https://ncbi.nlm.nih.gov/pubmed/25432537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu587 |
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